Princeton University says Princeton researchers find that high-fructose corn syrup prompts considerably more weight gain. "A Princeton University research team has demonstrated that all sweeteners are not equal when it comes to weight gain: Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same. In addition to causing significant weight gain in lab animals, long-term consumption of high-fructose corn syrup also led to abnormal increases in body fat, especially in the abdomen, and a rise in circulating blood fats called triglycerides. The researchers say the work sheds light on the factors contributing to obesity trends in the United States."
Update: Ars Technica goes through the study in some detail. "Although some of the results are suggestive, given the somewhat confusing and, in some cases, contradictory nature of the result, it would seem to be appropriate to interpret them with caution, and go back and start a larger population of rats on a study with a more consistent design. The authors haven't gone that route, as their conclusion (in its entirety) reads, "In summary, rats maintained on a diet rich in HFCS for 6 or 7 months show abnormal weight gain, increased circulating TG and augmented fat deposition. All of these factors indicate obesity. Thus, over-consumption of HFCS could very well be a major factor in the 'obesity epidemic,' which correlates with the upsurge in the use of HFCS.""
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