Monday, July 30, 2012

Darpa's Flu Fighters Ramp Up Veggie-Based Vaccines

Danger Room reports Darpa's Flu Fighters Ramp Up Veggie-Based Vaccines "The standard method of creating flu vaccine involves chicken eggs. Seriously: researchers combine the virus with a chicken embryo. But it takes months to ramp up production, and it takes a lot of eggs to cover a population. One estimate has it at nearly a billion eggs just to cover the U.S. alone. That’s a billion eggs you might not have during an outbreak.

Plant-based vaccines, however, are developed using ‘virus-like particles,’ which consist solely of protein and are non-infectious. They can’t spread between people, and they help produce anti-viral antibodies. To produce the particles, scientists synthesize the DNA of the flu virus, combine the flu DNA with bacteria, and then soak the plants with it. After soaking for a few minutes, the plants then start producing the flu-fighting particles. The DNA stays in the plant. The protein is then extracted and becomes the basis for a vaccine.

The most popular plant? Tobacco, as it grows relatively fast. The U.S. is also estimated to produce a heaping 450 metric tons of tobacco per year. And the whole process of turning tobacco into vaccines only takes a matter of weeks to complete. On a large enough scale, plant-based vaccines could be conceivably produced at 100 million vaccines a month. Egg-based vaccines, though, can take months just to develop."

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